From Roanoke, Virginia: Follow I-81 South to exit 74A in Tennessee (11W) toward Kingsport. Follow 11W into Kingsport and turn right onto US-23 North. Follow US-23 North to Duffield, Va. Turn left at the red light onto US-58 East. Follow US-58 East to US 421. Turn right onto US-421 to Pennington Gap, Va. Turn left at traffic light onto US-58 Alternate. Follow US-58 Alternate toward Jonesville, Va. Lee High School is located approximately 3 miles on the right.
From Cumberland or Harlan Kentucky: Follow US-421 South to Pennington Gap, Va. Turn right on US 58 Alternate heading West toward Jonesville, Va. Lee High School is located approximately 3 miles on the right.
From Corbin, Kentucky: Follow US-25E toward Cumberland Gap National park. At Cumberland Gap National Park take US 58 East toward Jonesville, Va. From Jonesville, take US-58 Alternate - go east toward Pennington Gap, Va. Lee high school is located approximately 3.5 miles on the left.
From Bluefield, Virginia: Follow US-19S to Hansonville, Va. Turn right onto US-58 Alternate heading West. Follow US-58 Alternate to Norton, Va. and take US-23 South to Big Stone Gap, Va. Take the 2nd exit into Big Stone Gap, US-23 Business/US 58 Alternate. Follow US-58 Alternate through Pennington Gap, VA. toward Jonesville, Va. Lee High School is located approximately 3 miles on the right.
From Tazewell, Tennessee: Follow US-25E North to Cumberland Gap National Park. At Cumberland Gap National Park take US-58 East to Jonesville, Va. From Jonesville take US-58 Alternate toward Pennington Gap, Va. Lee High School is located approximately 3.5 miles on the left.
From Jenkins, Kentucky: Follow US-23 South to Big Stone Gap, Va. Take the 2nd exit into Big Stone Gap, US-23 Bus/US-58 Alternate. Follow US-58 Alternate to Pennington Gap, Va. Continue following US 58 Alternate toward Jonesville. Lee High School is located approximately 3miles on the right.